Genotyping

ServiceXS has ample experience with SNP discovery, genotyping and screening at the same time. We are equipped to guide you in the diverse and fast developing SNP field. Scoring 100,000 SNPs in 10 samples requires a completely different approach than scoring 10 SNPs in 100,000 samples.

We can offer you unbiased advice and help you select the best approach to answering your research questions (click on the links below for more information).  

Our validated genotyping services: 

• Focused genotyping (Illumina BeadChip based)
  Illumina has fixed panels for different organisms (bovine, canine, ovine, porcine and maize) as well as different human panels, supporting a variety of applications such as candidate-gene studies in cancer, cardiovascular disease and more.
   
• Whole genome genotyping & CNV (Illumina BeadChip based)
  Illumina has fixed panels for human research, specific for cytogenetic analysis and/or CNV and LOH analysis. BeadChips are starting from 300,000 markers per sample to 2.5 million and the number is increasing still.
   
• Custom genotyping (Illumina BeadChip based)
  Illumina's GoldenGate technology is a customized genotyping service in our portfolio that provides solutions for a relatively low small number of SNPs per sample. The Infinium iSelect is ideal for larger projects. ServiceXS has become expert in both of these services. 
    
• CNV analysis (Fluidigm Technology based)
  Fluidigm's Dynamic Array with integrated fluidic circuits (IFCs) is suitable for copy number variation (CNV) studies. Using Fluidigms IFCs and Real-Time PCR methodology ServiceXS offers high throughput services with an extremely accurate quantification of CNV. In one single panel on the Dynamic Array IFC you can determine the difference between four and five copies.
    
• SNP discovery (Sequencing based)
  With Illumina or Helicos sequencing technology, ServiceXS can offer you SNP discovery and genotyping for any organism. With extensive data analysis, we can offer you customized production of specific SNP lists that are ready to use for the synthesis of custom genotyping assays for follow-up experiments.