ServiceXS is service provider for genomic laboratory services since 2002. Not only do we offer service-for-fee, but we also participate in research and development projects, aimed at future extensions of our service portfolio.
ServiceXS is actively involved in a number of national and international collaborations and consortia. Examples of our current and past collaborations:
|3Gb-TEST: Whole Genome testing (i.e. testing 3Gb of human sequence) will soon be a standard procedure in human genetics. The 3Gb-TEST consortium helps the community to be prepared for this change. ServiceXS is co-founder and co-chair of this FP7 coordinated and supported action.|
|BONE-NET: A Marcie-Curie project aimed at the identification of new genes and their regulators (e.g. microRNAs) that draw cancer cells to colonize bone. ServiceXS uses BONE-NET funding to develop single-cell assays on the Fluidigm platform.|
|DeCoDe: Decrease Colorectal Cancer Death - researching copy number variation in rectal carcinoma tumours.
We perform genotyping experiments on the Illumina and Fluidigm platforms. The CTMM-DeCoDe project was initiated in 2008 and is funded by a national scheme.
||EarlyNutrition: Long term effects of early nutrition on later health. ServiceXS' focus will be on the epigenetics. We will perform methylation analysis experiments using the Illumina HumanMethylation450K BeadChip. EarlyNytrition is an FP7-funded project.|
|Epistop: In 2013 ServiceXS joined the first prospective study on the pathophysiology of epilepsy. We will sequence the genome and the transcriptome of young patients with tuberous sclerosis before and after the onset of epilepsy (www.epistop.eu).|
|EUCID: The COST Action BM 1208 draws together researchers of all eight known human imprinting disorders (IDs) in an interdisciplinary pan-European network for human congenital IDs. ServiceXS is happy to contribute its knowledge on DNA modification analysis to this consortium (www.imprinting-disorders.eu).|
|FAST-SEQ: Focused Analysis of Solid Tumor material by single molecule SEQuencing. The project aims to develop assays for mutation detection in FFPE tumor material. ServiceXS is the network coordinator of this project. The project is funded by EuroTransBio.|
|GenoMEL: A consortium researching melanoma genetics. ServiceXS performed high-throughput genotyping experiments on melanoma tissues. This project yielded multiple Nature Genetics publications and ended in 2011.|
|HEALS: A project on exposomics. The ‘exposome’ represents the totality of exposures from conception onwards, simultaneously identifying, characterizing and quantifying the exogenous and endogenous exposures and modifiable risk factors that predispose to and predict diseases throughout a person’s life. (www.heals-eu.eu).|
|IDEAL: Integrated research on developmental determinants of Aging and Longevity - search for biomarkers determining longivity. ServiceXS will perform Affymetrix microarray analysis and develop assays for methylation analysis. IDEAL is an FP7-funded consortium.|
|iMODE-CKD: “Clinical and system –omics for the identification of the Molecular DEterminants of established Chronic Kidney Disease” is a Marie-Curie research project funded by the European Commission. ServiceXS performs expression profiling studies in kidney biopsies (www.imodeckd.org).|
|NGS-ProToCol: the second CTMM project performed by ServiceXS. We will utilize the Ion Proton™ technology to perform low-pass whole genome, full exome and RNA sequencing of 50 prostate tumors, 30 colorectal adenomas and 30 colorectal carcinomas.|
|OPTIBIOCAT: a FP7-funded project aimed at developing biocatalysts based on feruloyl esterases and glucuronoyl esterases for production of phenolic fatty- and sugar- esters with antioxidant activity for cosmetic industry. ServiceXS contributes genomics and transcriptomics expertise to this multidisciplinary consortium.|
|PGR secure: Novel characterization of crop wild relative and landrace resources as a basis for improved crop breeding. ServiceXS contributes to this FP7-funded project by sequencing Brassica species and the detection and analysis of SNPs in 15 different Brassica species.|
|SEQUON: Sequencing the Onion Genome. Unions are an important export product of the Netherlands. The Sequon project, which started in 2013, aims to perform de-novo sequencing of the union. The size of this genome is a real challenge, as it is five times larger than the human genome.|
|SysVasc: The FP7 project “Systems Biology to Identify Molecular Targets for Vascular Disease Treatment” started 2013. Although cardiovascular diseases are the number one killer in the Western world, its molecular causes are still mostly unknown. ServiceXS is proud to join this search for relevant biomarkers (www.sysvasc.eu).|
|TranCYST: ThanCYST is a Marie-Curie training Network focusing on Autosomal Dominant Polycystic Kidney Disease (PKD). ServiceXS performs molecular and system biology research on PKD mouse models.|
|Should you be interested in adding ServiceXS to your Horizon2020 or other collaboration initiatives as an SME, please contact us. We are always interested in innovative initiatives.