Affymetrix Gene Regulation Analysis

Tiling Arrays are the most comprehensive array tools available for discovering novel RNA transcripts or mapping sites of protein/DNA interaction in chromatin immunoprecipitation experiments.

All GeneChip Tiling Arrays feature:

• 25-mer oligonucleotides for optimal hybridization specificity
• The ability to run experiments and refine protocols in your own laboratory
• High-resolution arrays for the most accurate detection of protein/DNA interactions or novel transcript discovery

ChIP-on-chip

Chromatin immunoprecipitation (ChIP) assays have been used for over ten years to study protein/DNA interactions. ChIP protocols can now be used in conjunction with whole-genome tiled microarrays to understand DNA regulation by mapping sites of transcription factors binding to DNA. This powerful combination of ChIP and GeneChip Tiling Arrays has been used to map sites of protein/DNA interaction across entire chromosomes.

Click here for an overview of all Tiling Arrays available for ChIP-on-chip.

Transcript Mapping

Genome tiling arrays feature a neutral array design strategy to study entire genomes without respect to annotations. GeneChip brand Tiling Arrays have been used to discover novel transcripts and can be used to build annotations, particularly in genomic regions previously thought to be “genome deserts.” 

Click here for an overview of all Tiling Arrays available for Transcript Mapping.